The Side Effects of Lyrica and How to Avoid Them - Part 2

Continuing where we left off last time, we will be learning more about Lyrica, the other factors that may affect its components, and how to avoid its side effects.

Interactions with Other Drugs

Some complications may occur when taken with certain medications, such as those that slow down the neurological system, cause edema or fluid retention, or affect Lyrica's capacity to treat seizure disorders.

Numerous substances slow down nerve signals in the central nervous system, making them CNS depressants. They will make side effects like sedation, vertigo, and respiratory depression worse when used with Lyrica. These medications consist of:

  • Alcohol

  • Anti-nausea drugs

  • Antidepressants

  • Antiepileptic drugs

  • Antihistamines

  • Antipsychotics

  • Barbiturates

  • Benzodiazepines (such as lorazepam)

  • Gabapentin

  • General anesthetics

  • Marijuana

  • Muscle relaxants

  • Opioid pain relievers

  • Opioid pain relievers

  • Parkinson's disease medications

  • Sedatives and sleep aids

When Lyrica is given to prevent seizures, certain medications are never taken because they severely impair its capacity to do so. Amifampridine, dalfampridine, metoclopramide, maprotiline, bupropion, and muromonab-CD3 are some of the medications in this group. Pregabalin's therapeutic benefits in the treatment of seizure disorders can also be diminished by other types of medicines, necessitating monitoring and possible therapy adjustments. These medications consist of:

  • Stimulants, amphetamines, and medicines for ADHD

  • A few antiviral drugs

  • Antibiotics such as penicillins, fluoroquinolones, and carbapenems

  • Corticosteroids

  • Drugs that curb the appetite

  • A small class of pharmaceuticals known as MAO inhibitors, which also contains several antidepressants, antibiotics, and Parkinson's drugs

  • Theophyllines, drugs that open airways in people with asthma

Finally, since some medications cause swelling (edema) as a side effect, combining them with Lyrica considerably raises the risk of peripheral swelling and weight gain. These treatments include specific kinds of diabetes meds as well as ACE inhibitors (blood pressure medications).

Avoiding the Side Effects of Lyrica

Lyrica users frequently report negative side effects, particularly tiredness and vertigo. That said, there are some useful pieces of advice that may be followed to lessen or control the said side effects.

1. Inform Your Doctor about All Your Medical Conditions (If Any)

When prescribing Lyrica, a doctor or other healthcare professional will require a thorough medical history, in particular:

  • Suicidal ideation, depression, or mood issues

  • Kidney issues

  • Heart issues

  • Bleeding issues

  • Lung issues or breathing issues

  • Pregnancy or any plans to become pregnant

  • Breastfeeding

  • Plans to become a father

  • Any drug or alcohol misuse, past or present

  • Past experience with severe allergy reactions

2. Inform Your Doctor about All the Medications You Have Taken

It's crucial to give the doctor or healthcare provider prescribing Lyrica a thorough inventory of all prescription pharmaceuticals, over-the-counter medicines, treatments, and nutritional supplements being consumed, especially:

  • ACE inhibitors

  • Any drugs that cause sleepiness, drowsiness, dizziness, or problems with coordination

  • Diabetes medications

  • Opioid pain medications

3. Only Take Lyrica as Prescribed

Follow all the instructions supplied by a healthcare professional, printed in the medication guide, or on the prescription label. Except when advised to do so by a physician or other healthcare provider, never take more or less medication than is recommended.

4. Do Not Stop Your Lyrica Consumption All of a Sudden

Lyrica withdrawal effects can be unpleasant if suddenly stopped. Speak with a medical professional about the safest approach to stop taking Lyrica if the medication is not working or the side effects are intolerable.

5. Monitor for Any Changes in Your Mood

Take note that Lyrica users may possibly begin to have suicidal tendencies. Keep an eye out for sudden changes in mood, such as suicidal thoughts or feelings of melancholy, depression, anxiety, or panic attacks. Talk to a healthcare professional for advice if you have mood changes while taking Lyrica, as they might not go away completely.


Overall, the side effects of Lyrica can be serious and can include dizziness, drowsiness, and seizures. It is important to be aware of these potential side effects and to take the proper precautions to prevent them, including avoiding alcohol and other drugs.

You must also choose not to drive or handle heavy machinery, for the time being, just to be safe. That said, it is vital to talk to your doctor about any side effects you may experience while taking Lyrica.

If you are looking to learn more about Lyrica's side effects, look no further than our informative references here at Chorus for Life. We provide natural support for people taking pregabalin, an elegant blend of botanical powders to give you greater stability, clarity, and internal glow. Call us today for more information about Lyrica and its proper intake and dosage