Potential Risks of Taking Pregabalin for People with Health Conditions

Pregabalin is commonly used to treat pain, seizures, and anxiety. It is generally safe and well tolerated but may cause side effects such as dizziness, drowsiness, and swelling in the extremities. A few reports have been made of heart failure in elderly patients with chronic disease and a history of heart problems who were taking Pregabalin.

In this post, we're going to take a closer look at the potential risks of taking Pregabalin, especially for people with health conditions:

Pregabalin Intake for People with Kidney Problems

Pregabalin should be used with caution in people with kidney problems. This is because Pregabalin is removed from the body by the kidneys. People with kidney problems may have to take a lower dose of Pregabalin or may need to take it less often.

If you have problems with your kidneys and are thinking about taking Pregabalin, talk to your doctor first. They can help you determine if Pregabalin is suitable for you and what dose you should take.

Pregabalin Intake for People with Heart Problems

You must ask your doctor if this drug is safe for you to take, especially if you have heart problems like moderate or severe heart failure, as this can make your conditions worse.

Some symptoms to watch out for when taking Pregabalin when you have heart problems include:

  • swelling in your arms, legs, or feet

  • weight gain

  • fluid retention

Pregabalin Intake for People with Depression and Other Mental Health Issues

People suffering from depression or other mental health concerns should consult their doctor before taking Pregabalin. This is because of the possibility that the drug may increase the risk of having suicidal thoughts and harmful behaviors. If you are already taking Pregabalin, you and your loved ones should watch out for signs like worsening depression, unusual mood changes, erratic behavior, and thoughts of self-harming.

Pregabalin Intake for People with a History of Alcohol or Drug Misuse

If you have misused prescription medication, street drugs, or alcohol in the past, you need to seek your doctor's advice before taking Pregabalin. It is a controlled substance that could also increase the risk of misuse.

Pregabalin for People with Respiratory Problems

Those with breathing problems or lung disorders should be wary of taking Pregabalin as it could increase the risk of respiratory depression. Some issues that Pregabalin may aggravate include asthma, chronic obstructive pulmonary disease or COPD, and sleep apnea. Make sure that you clear it with your doctor before taking this drug.

Possible Heart Failure Associated with the Use of Pregabalin

Pregabalin (Lyrica) is a medication commonly used to treat various nerve pain and epilepsy forms. In recent years, it has also been approved for the treatment of anxiety and fibromyalgia. Although generally considered a safe and effective medication, some reports of possible heart failure associated with its use have been reported.

Some reports have identified cases of heart failure that were possibly associated with pregabalin use and compared these cases to those associated with other commonly used medications.

They found that the overall rate of heart failure was low but slightly higher in those taking Pregabalin than in those taking other medications. They also found that the risk of heart failure was highest in those taking the highest doses of Pregabalin.

Although studies did not prove that Pregabalin causes heart failure, they did show a possible link between the two. This is something that should be taken into consideration when deciding whether or not to take Pregabalin.


Pregabalin is generally considered safe for most people. However, there are some potential side effects that you should be aware of. These include dizziness, drowsiness, dry mouth, and swelling. If you or a loved one experiences side effects like the ones shared here, you should let a doctor know so they can be managed.

If you are already noticing side effects from taking Pregabalin (Lyrica), Chorus for Life may be able to help you. We offer natural support for people taking Pregabalin and experiencing its side effects. Find out more about Chorus and how it can help you today!